ST. LOUIS - Adam Wainwright and Yadier Molina made history with the first pitch of the game, then the record-setting battery helped the St. Louis Cardinals extend their NL Central lead by beating the Milwaukee Brewers 4-1 Wednesday night.
Wainwright and Molina started together for the 325th time, the most ever by a pitcher-catcher duo in the majors. The duo eclipsed the regular-season mark of 324 held by the Detroit Tigers pair of Mickey Lolich and Bill Freehan from 1963-1975.
Wainwright and Molina received a standing ovation from the crowd at Busch Stadium as they walked from the bullpen to the dugout prior to the game.
Towels with the No. 325 were given out to fans as they entered the ballpark.
Wainwright opened the game with a first-pitch strike to Christian Yelich, who out of respect for the moment, made no attempt to swing at the offering.
Wainwright and Molina made their first start together on April 6, 2007, in Houston. Wainwright recorded a 4-2 win in that game -- the first of his 213 victories with Molina behind the plate.
The 40-year-old Molina, a perennial Glove Glover, has indicated he will retire at the end of this season. The 41-year-old Wainwright has yet to make a decision on his future.
Wainwright (11-9) gave up just one run in five innings despite allowed eight hits and walked two. He struck out three and walked two in a 98-pitch stint.
Molina gave him a boost, throwing out Kolten Wong attempting to steal on the back end of a strikeout to end the third. Wainwright fanned Andrew McCutchen with a 74 mph curve and Molina still got Wong by plenty.
Molina put the Cardinals ahead for good with a tiebreaking single in the second.
Nolan Arenado and Lars Nootbaar both homered for the Cardinals, who have won three of four. They stretched their division lead to eight games over the second-place Brewers.
Milwaukee had a three-game winning streak snapped and remains two games behind San Diego in the race for the final wild-card spot in the NL.
Wainwright has thrown 2,141 of his 2,553 innings to Molina. He and Molina have teamed up to record 1,815 strikeouts.
Molina snapped a 1-all tie with an RBI single in the second.
Arenado hit his 29th homer in the second off Corbin Burnes (10-7).
Burnes gave up three runs on seven hits over seven innings. He struck out five and walked one.
Nootbaar pushed the lead to 3-1 with his 12th homer in the fifth.
Albert Pujols hit an RBI double in the eighth. He remains at 697 career home runs, fourth on the all-time list behind Barry Bonds (755), Hank Aaron (714) and Babe Ruth (715).
Pujols was hit on the right shoulder by a Burnes pitch in the sixth, but remained in the contest.
Ryan Helsley picked up his 17th save in 21 opportunities.
Yelich had two hits for the Brewers, who spent 92 days in first place in the NL Central earlier in this season.