Police said officers spotted a "suspicious" car near 76th and North. When officers tried to stop it, it took off and the pursuit began. It ended near 67th and Glendale in Milwaukee when the car disregarded a yield sign and crashed into a transport van around 3:20 p.m.
Two men, ages 29 and 31, were arrested. The injured driver stayed at the scene, a passenger ran off but was taken into custody after a "physical altercation" with an officer. All three people were taken to a hospital for treatment.
The driver of the transport van, a 73-year-old man, was also taken to a hospital with serious injuries. There were no passengers in the van.
Police said a third person is believed to have been involved and fled the scene.