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Nancy Guthrie: Glove DNA had no match in system
It has been 17 days since Nancy Guthrie went missing, and the sheriff of Pima County had an update on a piece of crucial DNA evidence in the case, as well as a message to the suspects. FOX 10's Justin Lum has more.
TUCSON, Ariz. - Feb. 17 marks the seventeenth day since Nancy Guthrie, the 84-year-old mother of NBC "Today" show host Savannah Guthrie, disappeared from her Tucson-area home. Investigators believe she was taken against her will.
Tuesday's latest updates
Afternoon Summary
In FOX 10 Investigator Justin Lum's one-on-one interview with Pima County Sheriff Chris Nanos, Nanos addressed some of the questions others had surrounding the case and its subsequent investigation.
"Your question really is on, again, the sheriff's belief from day one that Nancy's still here. You have no proof, nobody does, that she's not, that she is deceased," Sheriff Nanos said. "They ask me, ‘do I have proof of life?’ I ask them, ‘is there proof of death?’ I'm going to have that faith, and sometimes that faith, that hope is all we have. My team, 400 people out there in the field today, woke up this morning and went out there with the hope. And the belief that they're going to find Nancy, and she's gonna be okay. That family has that hope and belief. I'm not crushing that. We're gonna continue working this case every minute of every day, and we will find her, and we'll find you."
Nanos also had a message for the person responsible.
"The individual doing this. Just let her go. It will work out better for you in the long run. Trust me. Just let her go. Take her to a park. Take her, take her to the hospital. Just let her go," said Nanos.
‘Just let her go’: Sheriff issues plea to suspect in Nancy Guthrie's disappearance
DNA tests on a glove found near Nancy Guthrie’s home yielded no matches in a national database. Pima County Sheriff Chris Nanos, citing a continued rescue mission, urged suspects to release her at a hospital as the search enters week three.
5:00 p.m.
An official with the Pima County Sheriff's Department has released a statement with the latest updates. It reads, in part:
DNA: The DNA that was submitted to CODIS was from the set of gloves found 2 miles away. It did not trigger a match in the national CODIS database and did not match DNA found at the property. The DNA found at the property is being analyzed and further testing needs to be done as part of the investigation.
Investigators are currently looking into additional investigative genetic genealogy options for DNA evidence to check for matches. CODIS is one option of many databases that are available.
Tips:
• PCSD: The following numbers come from the PCSD 9-1-1 Communications Center. These are total calls, including tips coming in on the Nancy Guthrie investigation. Tips have been coming into the non-emergency line, administrative lines & 9-1-1. We do not track tips only. We’ve included last year’s numbers for comparison.
• Total Calls (9-1-1, Non-Emergency & Admin. Lines): 1-16 Feb 2026: 28,586
Compared to 1–16 Feb 2025: 18,451
• Total Non-Emergency Lines Calls: 1-16 Feb 2026: 20,968
Compared to 1–16 Feb 2025: 7,419
• FBI: The FBI's National Threat Operations Center (NTOC) routinely sees an influx in tips after any high-profile event. Any event mentioned in the news or online has the potential to result in an increase in incoming tips. NTOC has received more than 18,000 tips related to the Nancy Guthrie case since February 1. Threat intake examiners are working 24/7 to answer calls coming into the 1-800-CALL-FBI tipline and review those submitted at tips.fbi.gov.
Guthrie Residence: Investigators have been at the property today conducting follow-up. Details of that follow-up are not being shared at this time.
2:40 p.m.
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Pima County Sheriff Chris Nanos addressed recent rumors regarding the handling of evidence and his department's relationship with federal authorities in an interview following recent developments in a high-profile investigation. FOX 10's Justin Lum has the full one-one-one interview.
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The Pima County Sheriff's Department says investigators are working to locate Guthrie's pacemaker. They are also continuing to process evidence that was obtained from search warrants executed last week.
"The individuals who were questioned have been released, and no arrests have been made," PCSD said. "As this investigation continues, you can expect to see similar activity."
PCSD also says they have not confirmed the number of leads investigators are pursuing.
"Regarding gun shops, investigators are canvassing businesses and showing the doorbell video released by the FBI to determine whether the suspect appears familiar," PCSD said.
11: 28 a.m.
A DNA profile from a glove that was found two miles from Nancy Guthrie's home did not register any hits in the CODIS system, Pima County Sheriff Chris Nanos told FOX 10's Justin Lum.
11:12 a.m.
According to TMZ, a glove that was found two miles away from Nancy's home was tested for DNA in Florida and has been sent back to Arizona for further testing. Once the second testing is completed, the DNA profile found on the glove will be entered into CODIS, the national DNA database, to check for matches against convicted felons.
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What happened over the past few days?
Monday:
The Pima County Sheriff's Department issued the following statement from Sheriff Chris Nanos.
"To be clear…the Guthrie family - to include all siblings and spouses - has been cleared as possible suspects in this case. The family has been nothing but cooperative and gracious and are victims in this case.
Sheriff clears Nancy Guthrie’s family as suspects in her disappearance
Family members of Nancy Guthrie, including her children and their spouses, have been ruled out as suspects in her disappearance, the Pima County Sheriff's Department said Monday.
To suggest otherwise is not only wrong, it is cruel. The Guthrie family are victims plain and simple…please, I’m begging you the media to honor your profession and report with some sense of compassion and professionalism."
The Weekend:
The suspect's clothing seen in the surveillance video could've been purchased from Walmart, but the items are not exclusively sold there.
In a statement to FOX 10, PCSD said they "never stated that this was a burglary gone wrong. Any reports indicating otherwise are inaccurate. This remains a very active investigation."
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State Rep. slams Nancy Guthrie case ‘grifters’
As breakthroughs in the Nancy Guthrie case continue, Arizona State Rep. Alma Hernandez is speaking out against social media "grifters" she accuses of spreading misinformation for views. FOX 10's Taylor Wirtz reports.
Savannah Guthrie issued a new plea on Instagram for the safe return of Nancy, speaking to "whoever has her."
"I wanted to come on and... It's been two weeks since our mom was taken, and I just wanted to come on and say that we still have hope and we still believe. And I wanted to say to whoever has her or knows where she is, that it's never too late. And you're not lost or alone. And it is never too late to do the right thing. And we are here. We believe. And we believe in the essential goodness of every human being. And it's never too late."
On Feb. 15, the FBI released a statement saying that a glove recovered roughly two miles from the Guthrie residence appear to match the suspect's gloves in the surveillance camera from her front doorbell the night of her disappearance.
Results have since confirmed that the DNA profile did not match anyone in the CODIS database.
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Nancy Guthrie: DNA from glove yields no match
We have learned from a one-on-one interview with Pima County Sheriff Chris Nanos that the DNA profile recovered from a glove found 2 miles away from Guthrie's home did not register a hit in the CODIS system.
The backstory:
Guthrie went missing on the night of Jan. 31 and was reported missing on Feb. 1 when she didn't show up for church. Since her disappearance, the FBI has released footage of her alleged abductor at her doorstep.
Guthrie's family has pleaded on social media for her safe return, stating they are willing to pay a ransom following reports of several notes demanding payment in bitcoin.
PCSD and the FBI are working on finding Guthrie by searching rural and rigid terrain around the Tucson area, where Guthrie and her daughter, Annie, live. The sheriff's department is asking for anyone within a 2-mile radius of Guthrie's Catalina Foothills home to submit any footage they may have from Jan. 1 to Feb. 2 that they "deem out of the ordinary or important."
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Nancy Guthrie: Investigators seek help with video
As crews continue to search for Nancy Guthrie, investigators are also asking people who live in the area to check their surveillance video for anything unusual. FOX 10's Nicole Krasean has more, from Tucson.
On Feb. 12, the FBI released a description of the suspect seen in the doorbell camera footage. Additionally, the agency also increased its reward in the case to $100,000.
On Feb. 13, PCSD said DNA other than Nancy Guthrie's and "those in close contact to her" were collected from the property, and investigators are working to identify who it belongs to.
What you can do:
The FBI continues to urge anyone with information to contact its hotline at 1-800-CALL-FBI.
The Pima County Sheriff's Department has also set up a tipline where the community can submit information. A new online form is available for tips.
Nancy Guthrie: TMZ receives another email demanding money in exchange for suspect's identity
TMZ says they've received another email from a man demanding money in exchange for the identity of the person responsible for the alleged kidnapping of Nancy Guthrie.
Map of the area where Nancy Guthrie was last seen
The Source: The Pima County Sheriff's Department, the FBI, and previous FOX 10 reports.